Building a Better Infarct: Modulation of Collagen Cross-linking to Increase Infarct Stiffness and Reduce Left Ventricular Dilation post-Myocardial Infarction

Matrix metalloproteinase-9 (MMP-9) deletion attenuates collagen accumulation and dilation of the left ventricle (LV) post-myocardial infarction (MI); however the biomechanical mechanisms underlying the improved outcome are poorly understood. The aim of this study was to determine the mechanisms wher...

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Foilsithe in:J Mol Cell Cardiol
Main Authors: Voorhees, Andrew P., DeLeon-Pennell, Kristine Y., Ma, Yonggang, Halade, Ganesh V., Yabluchanskiy, Andriy, Iyer, Rugmani Padmanabhan, Flynn, Elizabeth, Cates, Courtney A., Lindsey, Merry L., Han, Hai-Chao
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530076/
https://ncbi.nlm.nih.gov/pubmed/26080361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.06.006
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