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The GTPase stimulatory activities of the neurofibromatosis type 1 and the yeast IRA2 proteins are inhibited by arachidonic acid.

Three proteins, GTPase activating protein (GAP), neurofibromatosis 1 (NF1) and the yeast inhibitory regulator of the RAS-cAMP pathway (IRA2), have the ability to stimulate the GTPase activity of Ras proteins from higher animals or yeast. Previous studies indicate that certain lipids are able to inhi...

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Detalhes bibliográficos
Main Authors: Golubić, M, Tanaka, K, Dobrowolski, S, Wood, D, Tsai, M H, Marshall, M, Tamanoi, F, Stacey, D W
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC453002/
https://ncbi.nlm.nih.gov/pubmed/1915269
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