Intravenous Infusion of Dexmedetomidine Combined Isoflurane Inhalation Reduces Oxidative Stress and Potentiates Hypoxia Pulmonary Vasoconstriction during One-Lung Ventilation in Patients

Inhalation anesthetic isoflurane inhibits hypoxia pulmonary vasoconstriction (HPV), while dexmedetomidine (Dex) could reduce the dose of isoflurane inhalation and potentiate HPV, but the mechanism is unclear. Inhibition of reactive oxygen species (ROS) production can favor HPV during one-lung ventil...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Xia, Rui, Xu, Jinjin, Yin, Hong, Wu, Huozhi, Xia, Zhengyuan, Zhou, Daiwei, Xia, Zhong-yuan, Zhang, Liangqing, Li, Haobo, Xiao, Xiaoshan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529970/
https://ncbi.nlm.nih.gov/pubmed/26273134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/238041
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