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High-throughput screening system for inhibitors of human Heat Shock Factor 2

Development of novel anti-cancer drug leads that target regulators of protein homeostasis is a formidable task in modern pharmacology. Finding specific inhibitors of human Heat Shock Factor 1 (hHSF1) has proven to be a challenging task, while screening for inhibitors of human Heat Shock Factor 2 (hH...

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Bibliographic Details
Published in:Cell Stress Chaperones
Main Authors: Smith, Levi M., Bhattacharya, Dwipayan, Williams, Daniel J., Dixon, Ivan, Powell, Nicholas R., Erkina, Tamara Y., Erkine, Alexandre M.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529873/
https://ncbi.nlm.nih.gov/pubmed/26003133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-015-0605-0
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