Donepezil attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells through SIRT1 activation

Cellular senescence of endothelial cells is a damage and stress response which induces pro-inflammatory, pro-atherosclerotic, and pro-thrombotic phenotypes. Donepezil is a drug used for the treatment of mild to moderate dementia of the Alzheimer’s disease (AD). The aim of the present study was to in...

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Dettagli Bibliografici
Pubblicato in:Cell Stress Chaperones
Autori principali: Zhang, Tao, Tian, Feng, Wang, Jing, Zhou, Shanshan, Dong, Xueqing, Guo, Kai, Jing, Jing, Zhou, Ying, Chen, Yundai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2015
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529865/
https://ncbi.nlm.nih.gov/pubmed/26194321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-015-0601-4
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