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Endodermal Wnt signaling is required for tracheal cartilage formation
Tracheobronchomalacia is a common congenital defect in which the walls of the trachea and bronchi lack of adequate cartilage required for support of the airways. Deletion of Wls, a cargo receptor mediating Wnt ligand secretion, in the embryonic endoderm using ShhCre mice inhibited formation of trach...
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Udgivet i: | Dev Biol |
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Main Authors: | , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529778/ https://ncbi.nlm.nih.gov/pubmed/26093309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.06.009 |
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