Ex vivo immunosuppressive effects of mesenchymal stem cells on Crohn’s disease mucosal T cells are largely dependent on indoleamine 2,3-dioxygenase activity and cell-cell contact

INTRODUCTION: Crohn’s disease (CD) is a disabling chronic enteropathy sustained by a harmful T-cell response toward antigens of the gut microbiota in genetically susceptible subjects. Growing evidence highlights the safety and possible efficacy of mesenchymal stem cells (MSCs) as a new therapeutic t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Stem Cell Res Ther
मुख्य लेखकों: Ciccocioppo, Rachele, Cangemi, Giuseppina C., Kruzliak, Peter, Gallia, Alessandra, Betti, Elena, Badulli, Carla, Martinetti, Miryam, Cervio, Marila, Pecci, Alessandro, Bozzi, Valeria, Dionigi, Paolo, Visai, Livia, Gurrado, Antonella, Alvisi, Costanza, Picone, Cristina, Monti, Manuela, Bernardo, Maria E., Gobbi, Paolo, Corazza, Gino R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529692/
https://ncbi.nlm.nih.gov/pubmed/26206376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0122-1
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