Endogenous Nodal promotes melanoma undergoing epithelial-mesenchymal transition via Snail and Slug in vitro and in vivo

Nodal, an important embryonic morphogen, has been reported to modulate tumorigenesis. Epithelial-mesenchymal transition (EMT) plays an important role in cancer metastasis. We have previously reported that recombinant Nodal treatment can promote melanoma undergoing EMT, but the effects of endogenous...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Guo, Qiang, Ning, Fen, Fang, Rui, Wang, Hong-Sheng, Zhang, Ge, Quan, Mei-Yu, Cai, Shao-Hui, Du, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529629/
https://ncbi.nlm.nih.gov/pubmed/26269769
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