Nek6 and Hif-1α cooperate with the cytoskeletal gateway of drug resistance to drive outcome in serous ovarian cancer

Hypoxia selects the most aggressive and drug-resistant clones in solid malignancies. One of the pivotal transcription factors induced by hypoxia is Hif-1α. However, in serous ovarian cancer (SEOC), Hif-1α expression is not a prognostic biomarker. This study aims to assess the hypothesis that the ser...

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Detaylı Bibliyografya
Yayımlandı:Am J Cancer Res
Asıl Yazarlar: Donato, Marta De, Fanelli, Mara, Mariani, Marisa, Raspaglio, Giuseppina, Pandya, Deep, He, Shiquan, Fiedler, Paul, Petrillo, Marco, Scambia, Giovanni, Ferlini, Cristiano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529609/
https://ncbi.nlm.nih.gov/pubmed/26269749
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