Glucagon-to-insulin ratio is pivotal for splanchnic regulation of FGF-21 in humans

BACKGROUND & AIMS: Fibroblast growth factor 21 (FGF-21) is a liver-derived metabolic regulator induced by energy deprivation. However, its regulation in humans is incompletely understood. We addressed the origin and regulation of FGF-21 secretion in humans. METHODS: By determination of arterial-...

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Publicat a:Mol Metab
Autors principals: Hansen, Jakob Schiøler, Clemmesen, Jens Otto, Secher, Niels Henry, Hoene, Miriam, Drescher, Andrea, Weigert, Cora, Pedersen, Bente Klarlund, Plomgaard, Peter
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529499/
https://ncbi.nlm.nih.gov/pubmed/26266087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.06.001
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