Atorvastatin reduces T-cell activation and exhaustion among HIV-infected cART-treated suboptimal immune responders in Uganda: a randomised crossover placebo-controlled trial

OBJECTIVE: T-cell activation independently predicts mortality, poor immune recovery and non-AIDS illnesses during combination antiretroviral therapy (cART). Atorvastatin showed anti-immune activation effects among HIV-infected cART-naïve individuals. We investigated whether adjunct atorvastatin ther...

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Detalhes bibliográficos
Publicado no:Trop Med Int Health
Main Authors: Nakanjako, Damalie, Ssinabulya, Isaac, Nabatanzi, Rose, Bayigga, Lois, Kiragga, Agnes, Joloba, Moses, Kaleebu, Pontiano, Kambugu, Andrew D., Kamya, Moses R., Sekaly, Rafick, Elliott, Alison, Mayanja-Kizza, Harriet
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529480/
https://ncbi.nlm.nih.gov/pubmed/25441397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tmi.12442
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