Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.

Germline mutations at the Dominant White Spotting (W) and Steel (Sl) loci have provided conclusive genetic evidence that c-kit mediated signal transduction pathways are essential for normal mouse development. We have analysed the interactions of normal and mutant W/c-kit gene products with cytoplasm...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Reith, A D, Ellis, C, Lyman, S D, Anderson, D M, Williams, D E, Bernstein, A, Pawson, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452940/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1714377/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07784.x
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