Three-dimensional structure of a mouse-adapted type 2/type 1 poliovirus chimera.

The crystal structure of V510, a chimeric type 2/type 1 poliovirus, has been determined at 2.6 A resolution. Unlike the parental Mahoney strain of type 1 poliovirus, V510 is able to replicate in the mouse central nervous system, due entirely to the replacement of six amino acids in the exposed BC lo...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Yeates, T O, Jacobson, D H, Martin, A, Wychowski, C, Girard, M, Filman, D J, Hogle, J M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452928/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1651227/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07772.x
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