Microglial Activation Promotes Cell Survival in Organotypic Cultures of Postnatal Mouse Retinal Explants

The role of microglia during neurodegeneration remains controversial. We investigated whether microglial cells have a neurotoxic or neuroprotective function in the retina. Retinal explants from 10-day-old mice were treated in vitro with minocycline to inhibit microglial activation, with LPS to incre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ferrer-Martín, Rosa M., Martín-Oliva, David, Sierra-Martín, Ana, Carrasco, Maria-Carmen, Martín-Estebané, María, Calvente, Ruth, Martín-Guerrero, Sandra M., Marín-Teva, José L., Navascués, Julio, Cuadros, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529135/
https://ncbi.nlm.nih.gov/pubmed/26252475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135238
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