The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication.

In Saccharomyces cerevisiae, DNA polymerase delta (POLIII), the product of the CDC2 (POL3) gene, possesses, in its N-terminal half, the well conserved 3-domain 3' to 5' exonuclease site. Strains selectively mutagenized in this site display a mutator phenotype detected as a drastically increased spon...

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Vydáno v:	EMBO J
Hlavní autoři:	Simon, M, Giot, L, Faye, G
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1648480/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07751.x
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