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The secondary structure of the ets domain of human Fli-1 resembles that of the helix-turn-helix DNA-binding motif of the Escherichia coli catabolite gene activator protein.

The ets family of eukaryotic transcription factors is characterized by a conserved DNA-binding domain of approximately 85 amino acids for which the three-dimensional structure is not known. By using multidimensional NMR spectroscopy, we have determined the secondary structure of the ets domain of on...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Liang, H, Olejniczak, E T, Mao, X, Nettesheim, D G, Yu, L, Thompson, C B, Fesik, S W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45290/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972119/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.24.11655
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