Chimeric molecules with multiple neurotrophic activities reveal structural elements determining the specificities of NGF and BDNF.

Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are two members of a family of neurotrophic factors which show both overlapping and distinct neurotrophic activities. Using site-directed mutagenesis, chimeric molecules were constructed where different combinations of sequences...

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Ibáñez, C F, Ebendal, T, Persson, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1991
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452896/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2065656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07743.x
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