Chimeric molecules with multiple neurotrophic activities reveal structural elements determining the specificities of NGF and BDNF.

Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are two members of a family of neurotrophic factors which show both overlapping and distinct neurotrophic activities. Using site-directed mutagenesis, chimeric molecules were constructed where different combinations of sequences...

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Библиографические подробности
Главные авторы: Ibáñez, C F, Ebendal, T, Persson, H
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC452896/
https://ncbi.nlm.nih.gov/pubmed/2065656
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