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Genetically based low oxygen affinities of felid hemoglobins: lack of biochemical adaptation to high-altitude hypoxia in the snow leopard
Genetically based modifications of hemoglobin (Hb) function that increase blood–O(2) affinity are hallmarks of hypoxia adaptation in vertebrates. Among mammals, felid Hbs are unusual in that they have low intrinsic O(2) affinities and reduced sensitivities to the allosteric cofactor 2,3-diphosphogly...
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| Gepubliceerd in: | J Exp Biol |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Company of Biologists
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528707/ https://ncbi.nlm.nih.gov/pubmed/26246610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.125369 |
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