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Microbuckling of fibrin provides a mechanism for cell mechanosensing

Biological cells sense and respond to mechanical forces, but how such a mechanosensing process takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show that cells in a fibrous matrix induce deformation fields that propagate over a longer range than predicted by linear elastic...

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Bibliografiske detaljer
Udgivet i:J R Soc Interface
Main Authors: Notbohm, Jacob, Lesman, Ayelet, Rosakis, Phoebus, Tirrell, David A., Ravichandran, Guruswami
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528600/
https://ncbi.nlm.nih.gov/pubmed/26040601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.0320
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