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Estimating T-cell repertoire diversity: limitations of classical estimators and a new approach
A highly diverse T-cell receptor (TCR) repertoire is a fundamental property of an effective immune system, and is associated with efficient control of viral infections and other pathogens. However, direct measurement of total TCR diversity is impossible. The diversity is high and the frequency distr...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528489/ https://ncbi.nlm.nih.gov/pubmed/26150657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0291 |
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