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An ex vivo model using human osteoarthritic cartilage demonstrates the release of bioactive insulin-like growth factor-1 from a collagen–glycosaminoglycan scaffold†

Biomimetic scaffolds hold great promise for therapeutic repair of cartilage, but although most scaffolds are tested with cells in vitro, there are very few ex vivo models (EVMs) where adult cartilage and scaffolds are co-cultured to optimize their interaction prior to in vivo studies. This study des...

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Publicado en:Cell Biochem Funct
Main Authors: Wardale, J, Mullen, L, Howard, D, Ghose, S, Rushton, N
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528234/
https://ncbi.nlm.nih.gov/pubmed/26059711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbf.3112
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