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Disassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase.

The nuclear lamina is an intermediate filament-type network underlying the inner nuclear membrane. At the onset of mitosis it depolymerizes, presumably in response to phosphorylation of the lamin proteins. Recently, cdc2 kinase, a major regulator of the eukaryotic cell cycle, was shown to induce lam...

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Bibliographic Details
Main Authors: Peter, M, Heitlinger, E, Häner, M, Aebi, U, Nigg, E A
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC452817/
https://ncbi.nlm.nih.gov/pubmed/1851086
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