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From G Protein-coupled Receptor Structure Resolution to Rational Drug Design

A number of recent technical solutions have led to significant advances in G protein-coupled receptor (GPCR) structural biology. Apart from a detailed mechanistic view of receptor activation, the new structures have revealed novel ligand binding sites. Together, these insights provide avenues for ra...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jazayeri, Ali, Dias, Joao M., Marshall, Fiona H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528114/
https://ncbi.nlm.nih.gov/pubmed/26100628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.668251
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