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Immune Tolerance Maintained by Cooperative Interactions between T Cells and Antigen Presenting Cells Shapes a Diverse TCR Repertoire

The T cell population in an individual needs to avoid harmful activation by self peptides while maintaining the ability to respond to an unknown set of foreign peptides. This property is acquired by a combination of thymic and extra-thymic mechanisms. We extend current models for the development of...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Best, Katharine, Chain, Benny, Watkins, Chris
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528093/
https://ncbi.nlm.nih.gov/pubmed/26300880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00360
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