Intraventricular fibrinolysis with tissue plasminogen activator is associated with transient cerebrospinal fluid inflammation: a randomized controlled trial

Locally administered tissue plasminogen activator (TPA) accelerates clearance of intraventricular hemorrhage (IVH), but its impact on neurologic outcomes remains unclear and preclinical research suggests it may have pro-inflammatory effects. We randomly allocated patients with ruptured cerebral aneu...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Kramer, Andreas H, Jenne, Craig N, Zygun, David A, Roberts, Derek J, Hill, Michael D, Holodinsky, Jessalyn K, Todd, Stephanie, Kubes, Paul, Wong, John H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528006/
https://ncbi.nlm.nih.gov/pubmed/25853905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.47
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