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PD-1 or PD-L1 Blockade Restores Antitumor Efficacy Following SSX2 Epitope-Modified DNA Vaccine Immunization

DNA vaccines have demonstrated antitumor efficacy in multiple preclinical models, but low immunogenicity has been observed in several human clinical trials. This has led to many approaches seeking to improve the immunogenicity of DNA vaccines. We previously reported that a DNA vaccine encoding the c...

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Bibliografski detalji
Izdano u:Cancer Immunol Res
Glavni autori: Rekoske, Brian T., Smith, Heath A., Olson, Brian M., Maricque, Brett B., McNeel, Douglas G.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527948/
https://ncbi.nlm.nih.gov/pubmed/26041735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0206
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