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Prevention of Nocturnal Elevation of Intraocular Pressure by Gene Transfer of Dominant-Negative RhoA in Rats
IMPORTANCE: We developed a gene transfer tool for the control of nocturnal elevated intraocular pressure (IOP). OBJECTIVE: To demonstrate that inhibiting the trabecular meshwork RhoA pathway by delivering a mutated, dominant-negative RhoA gene (dnRhoA) carried inside a long-expressing recombinant vi...
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| Publicado no: | JAMA Ophthalmol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527865/ https://ncbi.nlm.nih.gov/pubmed/25412195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2014.4747 |
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