Evidence of Subclinical mtDNA Alterations in HIV-Infected Pregnant Women Receiving Combination Antiretroviral Therapy Compared to HIV-Negative Pregnant Women

INTRODUCTION: Combination antiretroviral therapy (cART) can effectively prevent vertical transmission of HIV but there is potential risk of adverse maternal, foetal or infant effects. Specifically, the effect of cART use during pregnancy on mitochondrial DNA (mtDNA) content in HIV-positive (HIV+) wo...

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Veröffentlicht in:PLoS One
Hauptverfasser: Money, Deborah M., Wagner, Emily C., Maan, Evelyn J., Chaworth-Musters, Tessa, Gadawski, Izabelle, van Schalkwyk, Julie E., Forbes, John C., Burdge, David R., Albert, Arianne Y. K., Lohn, Zoe, Côté, Hélène C. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527775/
https://ncbi.nlm.nih.gov/pubmed/26247211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135041
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