Bisulfite Conversion of DNA: Performance Comparison of Different Kits and Methylation Quantitation of Epigenetic Biomarkers that Have the Potential to Be Used in Non-Invasive Prenatal Testing

INTRODUCTION: Epigenetic alterations, including DNA methylation, play an important role in the regulation of gene expression. Several methods exist for evaluating DNA methylation, but bisulfite sequencing remains the gold standard by which base-pair resolution of CpG methylation is achieved. The cha...

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Publicado en:PLoS One
Main Authors: Leontiou, Chrysanthia A., Hadjidaniel, Michael D., Mina, Petros, Antoniou, Pavlos, Ioannides, Marios, Patsalis, Philippos C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527772/
https://ncbi.nlm.nih.gov/pubmed/26247357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135058
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