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High Throughput Sequencing of Entamoeba 27nt Small RNA Population Reveals Role in Permanent Gene Silencing But No Effect on Regulating Gene Expression Changes during Stage Conversion, Oxidative, or Heat Shock Stress

The human parasite Entamoeba histolytica has an active RNA interference (RNAi) pathway with an extensive repertoire of 27nt small RNAs that silence genes. However the role of this pathway in regulating amebic biology remains unknown. In this study, we address whether silencing via 27nt small RNAs ma...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Zhang, Hanbang, Ehrenkaufer, Gretchen M., Manna, Dipak, Hall, Neil, Singh, Upinder
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527709/
https://ncbi.nlm.nih.gov/pubmed/26248204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134481
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