Cenicriviroc, a Novel CCR5 (R5) and CCR2 Antagonist, Shows In Vitro Activity against R5 Tropic HIV-2 Clinical Isolates

BACKGROUND: Maraviroc activity against HIV-2, a virus naturally resistant to different HIV-1 antiretroviral drugs, has been recently demonstrated. The aim of this study was to assess HIV-2 susceptibility to cenicriviroc, a novel, once-daily, dual CCR5 and CCR2 antagonist that has completed Phase 2b...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Visseaux, Benoit, Charpentier, Charlotte, Collin, Gilles, Bertine, Mélanie, Peytavin, Gilles, Damond, Florence, Matheron, Sophie, Lefebvre, Eric, Brun-Vézinet, Françoise, Descamps, Diane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527700/
https://ncbi.nlm.nih.gov/pubmed/26247470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134904
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