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Activation of LXRα but not LXRβ Protects Against Myocardial Ischemia/Reperfusion Injury

BACKGROUND: Liver-X-receptors, LXRα (NR1H3) and LXRβ (NR1H2), encode two different but highly homologous isoforms of transcription factors belonging to the nuclear receptor superfamily. Whether LXRα and LXRβ subtypes have discrete roles in the regulation of cardiac physiology/pathology is unknown. W...

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Detalhes bibliográficos
Publicado no:Circ Heart Fail
Main Authors: He, Qing, Pu, Jun, Yuan, Ancai, Lau, Wayne Bond, Gao, Erhe, Koch, Walter J., Ma, Xin-Liang, He, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527689/
https://ncbi.nlm.nih.gov/pubmed/25277999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001260
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