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Activation of LXRα but not LXRβ Protects Against Myocardial Ischemia/Reperfusion Injury

BACKGROUND: Liver-X-receptors, LXRα (NR1H3) and LXRβ (NR1H2), encode two different but highly homologous isoforms of transcription factors belonging to the nuclear receptor superfamily. Whether LXRα and LXRβ subtypes have discrete roles in the regulation of cardiac physiology/pathology is unknown. W...

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Détails bibliographiques
Publié dans:Circ Heart Fail
Auteurs principaux: He, Qing, Pu, Jun, Yuan, Ancai, Lau, Wayne Bond, Gao, Erhe, Koch, Walter J., Ma, Xin-Liang, He, Ben
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527689/
https://ncbi.nlm.nih.gov/pubmed/25277999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001260
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