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Activation of LXRα but not LXRβ Protects Against Myocardial Ischemia/Reperfusion Injury

BACKGROUND: Liver-X-receptors, LXRα (NR1H3) and LXRβ (NR1H2), encode two different but highly homologous isoforms of transcription factors belonging to the nuclear receptor superfamily. Whether LXRα and LXRβ subtypes have discrete roles in the regulation of cardiac physiology/pathology is unknown. W...

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Bibliografische gegevens
Gepubliceerd in:Circ Heart Fail
Hoofdauteurs: He, Qing, Pu, Jun, Yuan, Ancai, Lau, Wayne Bond, Gao, Erhe, Koch, Walter J., Ma, Xin-Liang, He, Ben
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527689/
https://ncbi.nlm.nih.gov/pubmed/25277999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001260
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