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N-myc disrupts protein kinase C-mediated signal transduction in neuroblastoma.

In neuroblastoma, amplification of the N-myc gene is closely correlated with increased metastatic ability. The mechanism by which N-myc acts to increase neuroblastoma malignancy is poorly understood as yet. It is shown here that transfection of N-myc in a neuroblastoma cell line causes suppression o...

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Bibliographic Details
Main Author: Bernards, R
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC452765/
https://ncbi.nlm.nih.gov/pubmed/1902412
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