Histamine-functionalized copolymer micelles as a drug delivery system in 2D and 3D models of breast cancer

Histamine functionalized block copolymers based on poly(allyl glycidyl ether)-b-poly(ethylene oxide) (PAGE-b-PEO) were prepared with different ratios of histamine and octyl or benzyl groups using UV-initiated thiol-ene click chemistry. At neutral pH, the histamine units are uncharged and hydrophobic...

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Pubblicato in:J Mater Chem B Mater Biol Med
Autori principali: Zhang, Yuning, Lundberg, Pontus, Diether, Maren, Porsch, Christian, Janson, Caroline, Lynd, Nathaniel A., Ducani, Cosimo, Malkoch, Michael, Malmström, Eva, Hawker, Craig J., Nyström, Andreas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527560/
https://ncbi.nlm.nih.gov/pubmed/26257912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4TB02051K
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