Direct and inverted DNA repeats associated with P-glycoprotein gene amplification in drug resistant Leishmania.

The H circle of Leishmania species contains a 30 kb inverted duplication separated by two unique DNA segments, a and b. The corresponding H region of chromosomal DNA has only one copy of the duplicated DNA. We show here that the chromosomal segments a and b are flanked by inverted repeats (198 and 1...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Ouellette, M, Hettema, E, Wüst, D, Fase-Fowler, F, Borst, P
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1672636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb08035.x
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