Impact of Expression Levels of Platinum-uptake Transporters Copper Transporter 1 and Organic Cation Transporter 2 on Resistance to Anthracycline/Taxane-based Chemotherapy in Triple-negative Breast Cancer

Adding platinum drugs to anthracycline/taxane (ANC-Tax)-based neoadjuvant chemotherapy (NAC) improves pathological complete response (pCR) rates in triple-negative breast cancer (TNBC). Copper transporter 1 (CTR1) and organic cation transporter 2 (OCT2) critically affect the uptake and cytotoxicity...

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Detalhes bibliográficos
Publicado no:Breast Cancer (Auckl)
Main Authors: Takeda, Risa, Naka, Ayano, Ogane, Naoki, Kameda, Yoichi, Kawachi, Kae, Shimizu, Satoru, Kamoshida, Shingo
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527352/
https://ncbi.nlm.nih.gov/pubmed/26309405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BCBCR.S27534
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