Glycogen synthase kinase-3 inhibition attenuates fibroblast activation and development of fibrosis following renal ischemia-reperfusion in mice

Glycogen synthase kinase-3β (GSK3β) is a serine/threonine protein kinase that plays an important role in renal tubular injury and regeneration in acute kidney injury. However, its role in the development of renal fibrosis, often a long-term consequence of acute kidney injury, is unknown. Using a mou...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Singh, Shailendra P., Tao, Shixin, Fields, Timothy A., Webb, Sydney, Harris, Raymond C., Rao, Reena
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527294/
https://ncbi.nlm.nih.gov/pubmed/26092126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020511
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