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Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast
Point mutations in the human MYO1E gene, encoding class I myosin Myo1e, are associated with focal segmental glomerulosclerosis (FSGS), a primary kidney disorder that leads to end-stage kidney disease. In this study, we used a simple model organism, fission yeast Schizosaccharomyces pombe, to test th...
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| Publicado no: | Dis Model Mech |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527290/ https://ncbi.nlm.nih.gov/pubmed/26092123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020214 |
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