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Multiple Drug Transport Pathways through human P-Glycoprotein()

P-glycoprotein (P-gp) is a plasma membrane efflux pump that is commonly associated with therapy resistances in cancers and infectious diseases. P-gp can lower the intracellular concentrations of many drugs to subtherapeutic levels by translocating them out of the cell. Because of the broad range of...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: McCormick, James W., Vogel, Pia D., Wise, John G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527178/
https://ncbi.nlm.nih.gov/pubmed/26125482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00018
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