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Sirtuins and Their Relevance to the Kidney
Sirtuins (silent information regulator 2 [Sir2] proteins) belong to an ancient family of evolutionary conserved nicotinamide adenine dinucleotide (NAD)(+)-dependent enzymes with deacetylase and/or mono-ADP-ribosyltransferase activity. They regulate DNA repair and recombination, chromosomal stability...
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| Published in: | J Am Soc Nephrol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527176/ https://ncbi.nlm.nih.gov/pubmed/20595677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010046 |
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