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Alternative Splicing Generates a Diacylglycerol Kinase α Transcript That Acts as a Dominant-Negative Modulator of Superoxide Production in Localized Aggressive Periodontitis

BACKGROUND: Diacylglycerol (DAG), levels of which are tightly regulated by diacylglycerol kinases (DGKs), is a lipid mediator linked to key biologic functions. Members of the DGK family undergo alternative splicing, generating the protein diversity necessary to control different intracellular DAG po...

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Bibliografiske detaljer
Udgivet i:J Periodontol
Main Authors: Batista, Eraldo L., Kantarci, Alpdogan I., Hasturk, Hatice, Van Dyke, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527154/
https://ncbi.nlm.nih.gov/pubmed/24171497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1902/jop.2013.130468
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