A nucleation--elongation mechanism for the self-assembly of side polar sheets of smooth muscle myosin.

Self-assembled filaments of smooth muscle myosin were observed by low dose electron microscopy to be flat side-polar sheets, in which the component molecules appeared straight and close-packed. Fraying experiments released small oligomers, in which molecules were staggered in parallel by about +/- 1...

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Udgivet i:EMBO J
Main Authors: Cross, R A, Geeves, M A, Kendrick-Jones, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452712/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2009856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb08006.x
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