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ERBB2 Emerges as a New Target for Colorectal Cancer

ERBB2 mutations and amplifications are present in 7% of colorectal cancers. The presence of these alterations may be a marker of resistance to anti-EGFR therapy and, more importantly, could help identify patients who would benefit from ERBB2-directed therapy.

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Pectasides, Eirini, Bass, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527096/
https://ncbi.nlm.nih.gov/pubmed/26243861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0730
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