Formation of a thermodynamically metastable structure containing hairpin II is critical for infectivity of potato spindle tuber viroid RNA.

The functional relevance of a hairpin II-containing structure of viroid RNA was studied by site-directed mutagenesis, thermodynamic calculations, experimental denaturation curves and infectivity tests. Hairpin II is formed during thermal denaturation of circular viroids or as part of a metastable st...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Loss, P, Schmitz, M, Steger, G, Riesner, D
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1991
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452707/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2001685/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb08002.x
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