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The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG.

The pim-1 gene is frequently found activated by proviral insertion in murine T cell lymphomas. Overexpression of pim-1 in lymphoid cells by transgenesis formally proved its oncogenic potential. The pim-1 cDNA sequence predicts that both murine and human pim-1 encode a 34 kd protein with homology to...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Saris, C J, Domen, J, Berns, A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452698/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1825810/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07994.x
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