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Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo

Targeted inhibition of protein kinase C (PKC) inhibits hepatocellular carcinoma (HCC) proliferation and metastasis. We previously reported the cytotoxicity of a series of synthetic phenyl-substituted polyoxygenated xanthone derivatives against human HCC. In the current study, the most potent natural...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yuan, Xing, Chen, Hao, Li, Xia, Dai, Ming, Zeng, Huawu, Shan, Lei, Sun, Qingyan, Zhang, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526861/
https://ncbi.nlm.nih.gov/pubmed/26245668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12889
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