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Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur.

Cloning of the MET19 gene revealed that it encodes the glucose-6-phosphate dehydrogenase from yeast. Sequence analysis showed a high degree of similarity between the yeast and the human enzymes. The cloned gene has allowed the construction of a glucose-6-phosphate dehydrogenase null mutant. The only...

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Autors principals: Thomas, D, Cherest, H, Surdin-Kerjan, Y
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC452682/
https://ncbi.nlm.nih.gov/pubmed/2001672
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