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Fine mapping of the uterine leiomyoma locus on 1q43 close to a lncRNA in the RGS7-FH interval

Mutations in fumarate hydratase (FH) on chromosome 1q43 cause a rare cancer syndrome, hereditary leiomyomatosis and renal cell cancer (HLRCC), but are rare in nonsyndromic and common uterine leiomyoma (UL) or fibroids. Studies suggested that variants in FH or in a linked gene may also predispose to...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Aissani, Brahim, Zhang, Kui, Mensenkamp, Arjen R, Menko, Fred H, Wiener, Howard W
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526794/
https://ncbi.nlm.nih.gov/pubmed/26113603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-15-0208
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