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Origins, genetic landscape, and emerging therapies of small cell lung cancer

Lung cancer is the leading cause of cancer deaths, with small cell lung cancer (SCLC) representing the most aggressive subtype. Standard treatments have not changed in decades, and the 5-year survival rate has remained <7%. Genomic analyses have identified key driver mutations of SCLC that were s...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Semenova, Ekaterina A., Nagel, Remco, Berns, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526731/
https://ncbi.nlm.nih.gov/pubmed/26220992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.263145.115
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