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Tuberculosis Drug Development: History and Evolution of the Mechanism-Based Paradigm 

Modern tuberculosis (TB) chemotherapy is widely viewed as a crowning triumph of anti-infectives research. However, only one new TB drug has entered clinical practice in the past 40 years while drug resistance threatens to further destabilize the pandemic. Here, we review a brief history of TB drug d...

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Pubblicato in:Cold Spring Harb Perspect Med
Autori principali: Chakraborty, Sumit, Rhee, Kyu Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526730/
https://ncbi.nlm.nih.gov/pubmed/25877396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a021147
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